Normalised compression distance and evolutionary distance of genomic sequences: comparison of clustering results
- Autori: Rosa, M; Gaglio, S; Rizzo, R; Urso, A
- Anno di pubblicazione: 2009
- Tipologia: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/103785
Abstract
Genomic sequences are usually compared using evolutionary distance, a procedure that implies the alignment of the sequences. Alignment of long sequences is a time consuming procedure and the obtained dissimilarity results is not a metric. Recently, the normalised compression distance was introduced as a method to calculate the distance between two generic digital objects and it seems a suitable way to compare genomic strings. In this paper, the clustering and the non-linear mapping obtained using the evolutionary distance and the compression distance are compared, in order to understand if the two distances sets are similar.