3D collagen matrix improves islets of Langerhans differentiation and function
- Autori: Salamone, M; Saladino, S; Cuttitta, A; Ghersi, G
- Anno di pubblicazione: 2014
- Tipologia: eedings
- OA Link: http://hdl.handle.net/10447/99906
Abstract
The importance of preserve cell-cell contact and cell-matrix interaction are both fundamental for maintain the differentiation state. We use both standardized method of isolation and culture in 3D matrix which improves islet cell survival and function for more than one week in colture.