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GIOVANNI GRASSO

Cisternostomy: A Timely Intervention in Moderate to Severe Traumatic Brain Injuries: Rationale, Indications, and Prospects

  • Autori: Cherian, I.; Burhan, H.; Dashevskiy, G.; Motta, S.J.H.; Parthiban, J.; Wang, Y.; Tong, H.; Torregrossa, F.; Grasso, G.
  • Anno di pubblicazione: 2019
  • Tipologia: Articolo in rivista
  • OA Link: http://hdl.handle.net/10447/413776

Abstract

Traumatic brain injury (TBI) represents a major public health concern worldwide, with no significant change in its epidemiology over the last 30 years. After TBI, the primary injury induces irreversible brain damage, which is untreatable. The subsequent secondary injury plays a critical role in the clinical prognosis because without effective treatment it will provide additional tissue damage. The resulting scenario is the rise in intracranial pressure (ICP) with the development of progressive neurological deficits. Current optimal management is based on a progressive, target-driven approach combining both medical and surgical treatment strategies among which is decompressive hemicraniectomy. With the advent of technology, research in the glymphatic pathways, and advances in microscopic surgery, a novel surgical technique—the cisternostomy—has emerged that holds promise in managing rising ICP in TBI-affected patients. In this article we describe the rationale for cisternostomy, an emerging microneurosurgical approach for the management of moderate to severe TBI. © 2019 Elsevier Inc.