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PATRIZIA DIANA

Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine,a new ring system as potential COX inhibitor

  • Autori: Migliara, O.; Spano', V.; Parrino, B.; Ciancimino, C.; Diana, P.
  • Anno di pubblicazione: 2012
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: [1,2,6]Benzothiadiazocine, 1,4-dihydropyrazolo[4,3-c][1,2,6benzothiadiazocin-11(10H)one 5,5-dioxides, pyrazole, COX inhibitors
  • OA Link: http://hdl.handle.net/10447/63019

Abstract

Derivatives of the new ring system 1,4-dihydropyrazolo[4,3-c][1,2,6] benzothiadiazocin-11(10H)one 5,5-dioxide were synthesized in five or six steps in 57-66% overall yields and tested as COX inhibitors.