ESAT-6 peptide recognition by bovine CD8+ lymphocytes of naturally infected cows in herds from southern Italy.
- Autori: VITALE F; REALE S; PETROTTA E; CARACAPPA S; BARERA A; LA MANNA MP; MACALUSO P; CACCAMO N; DIELI F; VORDERMEIER HM; SIRECI G; SALERNO A
- Anno di pubblicazione: 2006
- Tipologia: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/6042
The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8(+) T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8' T cells recognized 10 out of 11 ESAT-6 peptides tested