Salta al contenuto principale
Passa alla visualizzazione normale.

FRANCESCO DIELI

Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

  • Autori: Ciccia, Francesco; Guggino, Giuliana; Zeng, Michael; Thomas, Ranjeny; Ranganathan, Vidya; Rahman, Arifur; Alessandro, Riccardo; Rizzo, Aroldo; Saieva, Laura; Macaluso, Federica; Peralta, Sergio; Di Liberto, Diana; Dieli, Francesco; Cipriani, Paola; Giacomelli, Roberto; Baeten, Dominique; Haroon, Nigil
  • Anno di pubblicazione: 2018
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: CX3CR1+ monocytes; IL-23; ILC3; TL1A; gut inflammation
  • OA Link: http://hdl.handle.net/10447/295625

Abstract

Gut derived ILC3 have been demonstrated to participate in AS pathogenesis. CX3CR1+ mononuclear phagocytes (MNP) have been demonstrated to modulate ILC3 function in the gut. The aim of this study was to study the role of pro-inflammatory CX3CR1+ CD59+ MNP in modulating ILC3 function in AS patients.