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GIUSEPPINA CANDORE

Immunological and immunogenetic markers in sporadic Alzheimer's disease

  • Authors: LIO D; SCOLA L; COLONNA ROMANO G; CANDORE G; CARUSO C
  • Publication year: 2006
  • Type: Articolo in rivista (Articolo in rivista)
  • Key words: Alzheimer’s disease, cytokines, immunogenetics, inflammation, proteomics
  • OA Link: http://hdl.handle.net/10447/17627

Abstract

Background: Common polymorphisms of genes controlling inflammation-modulating cytokines and acute-phase proteins which play important roles in the pathogenesis of Alzheimer''s disease (AD) have been shown to be associated with AD. Aims: The immunological and immunogenetic markers potentially useful for the AD risk evaluation and diagnosis are briefly reviewed. Conclusion: The state-of-the-art of immunological and immunogenetic markers of AD indicates that new tools and strategies are necessary to identify gene products useful as diagnostic tools.