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GIUSEPPE CRESCIMANNO

Effects of apomorphine on orienting reaction in the rat

  • Autori: Casarrubea, M.; Sorbera, F.; Crescimanno, G.
  • Anno di pubblicazione: 2009
  • Tipologia: Capitolo o Saggio (Capitolo o saggio)
  • Parole Chiave: Dopamine; A9 and A10 neurons; Head turning; apomorphine; sensorimotor integration
  • OA Link: http://hdl.handle.net/10447/50585

Abstract

Aim of the research was to study the possible relationship between rapid apomorphine-induced modifications of midbrain dopaminergic neuron activity and rapid modifications of a motor response triggered by sensory stimuli (sensory-motor integration. Following apomorphine administration, ANOVA test revealed significant decrease of head turning latency and duration. A change on dopamine release, leading to an inhibition or facilitation of dopamine-mediated responses to environmental stimuli, may be hypothesized.