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GIUSEPPE CRESCIMANNO

Prior test experience produces changes of t-patterns spatial distribution in the elevated plus maze test

  • Autori: Casarrubea, M.; Faulisi, F.; Santangelo, A.; Roy, V.; Arabo, A.; Magnusson, M.; Sorbera, F.; Crescimanno, G.
  • Anno di pubblicazione: 2014
  • Tipologia: Proceedings (TIPOLOGIA NON ATTIVA)
  • OA Link: http://hdl.handle.net/10447/96004

Abstract

Aim of present research was to investigate in male Wistar rats whether a prior elevated plus maze experience modifies the temporal structure of the behavioral response following a retest applied after 24h. Video files were coded by means of a software coder and event log files generated for each subject were analyzed by means of a specific software for temporal pattern analysis (Theme). Present research shows a clear reduction of the number of t-patterns from trial one to trial two. This reduction is provoked by the disappearance of t-patterns consisting of behavioral elements occurring in the unprotected zones of the maze. The results suggest that the previous experience in the maze causes learning-dependent behavioral changes inducing a more clear-cut response to environmental anxiogenic conditions.