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GASPARE CUCINELLA

A randomized comparison of endometrial laser intrauterine thermotherapy and hysteroscopic endometrial resection

  • Autori: Perino, A.; Castelli, A.; Cucinella, G.; Biondo, A.; Pane, A.; Venezia, R.
  • Anno di pubblicazione: 2004
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/34410

Abstract

Objective: To investigate the difference of long-term amenorrhea rate in patients with menorrhagia treated by endometrial laser intrauterine thermal therapy (ELITT), a new nonhysteroscopic endometrial ablation proce- dure, versus transcervical hysteroscopic endometrial resection (TCRE). Design: Randomized clinical study. Healthy volunteers in an academic research environment. Setting: Academic teaching hospital. Patient(s): Premenopausal women with abnormal uterine bleeding. Intervention(s): Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure. Main Outcome Measure(s): Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate. Result(s): At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure. Conclusion(s): Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.