STRESS, CHAPERONI MOLECOLARI E MALATTIE INFIAMMATORIE CRONICHE DELL'INTESTINO
- Autori: CAPPELLO, F; TOMASELLO, G
- Anno di pubblicazione: 2011
- Tipologia: Articolo su rivista (Articolo in rivista)
- Parole Chiave: chaperons, HSP60, IBD
This brief article is focused on HSP60, a very important molecular chaperon for cell surviving, involved in the pathogenesis of several degenerative, autoimmune, and neoplastic disorders. Recent reports confer unravelling role in IBD pathogenesis. involvement of HSP60 in CD and UC development has been recently confirmed. in fact HSP60 levels increase in mucosal epithelium and also in lamina propria of affected subjects.