The prevalence of post-thyroidectomy chronic asthenia: a prospective cohort study
- Autori: Scerrino, G.; Melfa, G.; Raspanti, C.; Attard, A.; Mazzola, S.; Gullo, R.; Bonventre, S.; Attard, M.; Cocorullo, G.; Gulotta, G.
- Anno di pubblicazione: 2017
- Tipologia: Articolo in rivista (Articolo in rivista)
- Parole Chiave: Chronic asthenia; Fatigue; Hemithyroidectomy; Total thyroidectomy; Surgery
- OA Link: http://hdl.handle.net/10447/246204
Purpose: Chronic asthenia (CA) is complained by some patients that have undergone thyroid surgery. We evaluate its impact in patients undergoing unilateral or bilateral thyroidectomy, the trend during a 1-year follow-up, and the possible risk factors. Methods: A prospective, cohort study was carried out on 263 patients scheduled for thyroidectomy from 2012 and 2014. Exclusion criteria were as follows: Gravesâ disease, malignancies requiring radioiodine therapy, post-surgical hypoparathyroidism, laryngeal nerve palsy, abnormal pre- and post-operative thyroid hormone levels, and BMI outside the normal range. Demographics; smoking and alcoholism addiction; cardiac, pulmonary, renal, and hepatic failure; diabetes; anxiety; and depression were recorded. The Brief Fatigue Inventory (BFI) was used to evaluate CA and its possible association with these comorbidities 6 and 12Â months after thyroidectomy. Results: One hundred seventy-seven patients underwent total thyroidectomy (TT), 54 hemithyroidectomy (HT). Thirty-two patients were not recorded because of the onset of exclusion criteria. In the 6Â months after thyroidectomy, in the TT group, 64 patients (36.16%) reported an impairment in the BFI score and only 1 in the TL group. The mean BFI score changed from 1.663(Â±1.191) to 2.16 (Â±11.148) in the TT group, from 1.584 (Â±1.371) to 1.171 (Â±1.093) in the TL group (pÂ