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MAURIZIO BRUNO

Labdane diterpenoids from Marrubium globosum ssp. libanoticum

  • Autori: RIGANO D; GRASSIA A; BRUNO M; ROSSELLI S; PIOZZI F; FORMISANO C; ARNOLD NA; SENATORE F
  • Anno di pubblicazione: 2006
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/30606

Abstract

From the aerial parts of Marrubium globosum ssp. libanoticum, seven labdane diterpenoids were isolated. Three of them are new natural products [(13R)-9R,13R-epoxylabda-6â(19),16(15)-diol dilactone (2), deacetylvitexilactone (7), marrulanic acid (8)], whereas the other four, namely, (13S)-9R,13R-epoxylabda-6â(19),16(15)-diol dilactone (1), cyllenin A (3), 15-epi-cyllenin A (4), and marrulibanoside, are previously known compounds. The structures of 2, 7, and 8 were determined by spectroscopic and chemical methods.