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Can the TLR-4-Mediated Signaling Pathway Be a Key Inflammatory Promoter for Sporadic TAA?

  • Autori: Ruvolo, G.; Pisano, C.; Candore, G.; Lio, D.; PALMERI DI VILLALBA, C.; Maresi, E.; Balistreri, C.
  • Anno di pubblicazione: 2014
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • OA Link:


vascular remodeling (VR) and medial degeneration (MD) occur as pathological entities responsible principally for the sporadic TAA onset. Little is known about their genetic, molecular, and cellular mechanisms. Recent evidence is proposing the strong role of a chronic immune/inflammatory process in their evocation and progression.