Increased expression of interleukin-22 in patients with giant cell arteritis
- Authors: Zerbini, A.; Muratore, F.; Boiardi, L.; Ciccia, F.; Bonacini, M.; Belloni, L.; Cavazza, A.; Cimino, L.; Moramarco, A.; Alessandro, R.; Rizzo, A.; Parmeggiani, M.; Salvarani, C.; Croci, S.
- Publication year: 2017
- Type: Articolo in rivista (Articolo in rivista)
- Key words: arterial remodelling; autoimmunity; giant cell arteritis; inflammation; interleukin-22; pathogenesis
- OA Link: http://hdl.handle.net/10447/245703
Abstract
GCA is characterized by arterial remodelling driven by inflammation. IL-22 is an attractive cytokine which acts at the crosstalk between immune and stromal cells. We hypothesized that IL-22 might be induced in GCA and might be involved in disease pathogenesis.