The carriers of the A/G-G/G allelic combination of the c.2039 A>G and c.-29 G>A FSH receptor polymorphisms retrieve the highest number of oocytes in IVF/ICSI cycles
- Autori: Allegra, A.; Marino, A.; Raimondo, S.; Maiorana, A.; Gullo, S.; Scaglione, P.; Volpes, A.; Alessandro, R.
- Anno di pubblicazione: 2016
- Tipologia: Articolo in rivista (Articolo in rivista)
- Parole Chiave: COH; FSH receptor polymorphisms; IVF/ICSI; Treatment personalization
- OA Link: http://hdl.handle.net/10447/207390
Abstract
The objective of this study was the elucidation of the possible role of the single-nucleotide polymorphisms (SNP) at position -29 and 2039 of the FSH receptor gene (FSHR) as independent predictive markers of ovarian response. Indeed, the tailoring of reproductive treatments is crucial for both maximizing the success of IVF patients and obtaining a reduction in hypo- or hyper-response rates.