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S-100 calcium binding proteins as potential markers for breast cancer metastasis.

  • Autori: Pucci, I.; Cancemi, P.; DI CARA, G.; Albanese, N.; Marabeti, M.; Costantini, F.; Musso, R.; Taormina, P.; Marrazzo, A.; Minafra, A.
  • Anno di pubblicazione: 2009
  • Tipologia: Proceedings (TIPOLOGIA NON ATTIVA)
  • Parole Chiave: S-100 proteins, breast cancer
  • OA Link:


The S-100 family of calcium-binding proteins includes about 20 members of low molecular weight characterized by two consecutive EF hands domains. They make interactions with cellular target proteins in a calcium-dependent manner; therefore they are thought to regulate a variety of physiological functions, such as cell proliferation, signal transduction, cell adhesion, motility as well as cancer metastasis.