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Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination

  • Autori: Indelicato, S.; Bongiorno, D.; Indelicato, S.; Ceraulo, L.; Tranchina, E.; Avellone, G.; Arcadipane, C.; Giambartino, F.
  • Anno di pubblicazione: 2014
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: anesthetics, desflurane, sevoflurane,hexafluoroisopropanol
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In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter’shepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetics exposition on the urine levels of a small population of surgical operators has been performed and results are briefly discussed.